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NFL 2022 Week 4: ‘Monday Night Football’ Los Angeles Rams vs. San Francisco 49ers picks

Let’s watch some football!

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NFL, Rams, 49ers, NFC Championship Wally Skalij/Los Angeles Times via Getty Images

Week 4 of the 2022 season is almost complete, and the Washington Commanders lost their third game in a row yesterday and looked worse doing it. Washington went down to Dallas and could only score 10 points while giving up 25. They are now in last place in the division, and spiraling to the bottom of the league.

Tonight’s game is an NFC West matchup between the the Los Angeles Rams and the San Francisco 49ers. Jimmy Garoppolo is the 49ers starter again after Trey Lance’s season-ending ankle injury. He finished the game with a win two weeks ago, but lost to the Broncos last week. The Rams are the defending Super Bowl Champions and are looking for a return trip to the big game in February.

Who: Los Angeles Rams (2-1) at San Francisco 49ers (1-2)

Where: Levi’s Stadium | Santa Clara, CA

When: October 3, 2022, 8:15 p.m.


Joe Buck(play-by-play)

Troy Aikman(analyst)

Lisa Salters (sideline)

Online Stream: Fubo.TV, ESPN+

DraftKings Sportsbook odds: 49ers -2, 42 O/U

Prediction: Rams 23 - 49ers 17

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