The game will played on Oct. 31, and the 49ers will be listed as the home team.
"For the past three years we have seen the extraordinary passion that exists for NFL football in the U.K.," NFL commissioner Roger Goodell said in a statement. "We want to continue to build on that passion by strengthening our ties to our existing U.K. fans and creating new ones."
The game between the five-time Super Bowl champion 49ers and two-time winner Broncos may not be the only one in Britain next season.
"The NFL will continue to explore the possibility of playing a second game in the UK in 2010," the NFL said.
Thank god its not, hopefully they won't do a second game involving us either.